Postdoctoral position in the Shcheglovitov Lab to study human brain development anddisease using stem cell-derived brain organoidsWe are looking for a motivated and creative individual to join our group as a postdoctoralresearch associate to study the development of functional neural circuits under normal andpathological conditions using human stem cell-derived organoids (Wang et al., NatureCommunications 2022). We particularly welcome applications from recent/ready-to-graduatePh.D. students with backgrounds in cellular, molecular, or system neuroscience and substantialexperience with electrophysiology and/or calcium imaging. If you are interested in thisopportunity, please send your CV and cover letter briefly describing your research interests andmotivation to Dr. Shcheglovitov (alexsh@neuro.utah.edu).The following links provide more information about life in the Shcheglovitov lab and Salt LakeCity, Utah:Shcheglovitov lab: http://shcheglovitov-lab.utah.eduUtah: https://uofuhealth.utah.edu/living-in-utahRelevant publications:Yang et al., 2023: Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatricbipolar disorder medRxiv: https://doi.org/10.1101/2022.05.06.22274499Wang et. al., 2022: Modeling autism-associated SHANK3 deficiency using humancortico-striatal organoids generated from single neural rosettes Nature Communicationshttps://doi.org/10.1038/s41467-022-33364-zChiola, Napan, Wang et al., 2021: Defective AMPA-mediated synaptic transmission andmorphology in human neurons with hemizygous SHANK3 deletion engrafted in mouseprefrontal cortex Molecular Psychiatry https://doi.org/10.1038/s41380-021-01023-2Shcheglovitov A et al., 2013: Shank3 and IGF1 Restore Synaptic Deficits in Neuronsfrom 22q13 Deletion Syndrome Patients, Nature https://doi.org/10.1038/nature12618Reviews:Chiola et., 2021: iPSC toolbox for understanding and repairing disrupted brain circuits inautism Molecular Psychiatry https://doi.org/10.1038/s41380-021-01288-7Yang & Shcheglovitov 2020: Probing disrupted neurodevelopment in autism usinghuman stem cell-derived neurons and organoids: An outlook into future diagnostics anddrug development Dev Dynamics: https://doi.org/10.1002/dvdy.100